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Diagnosis of anal dysplasia the diagnosis of anal dysplasia may be made by performing an anal pap smear. Just like a cervical pap smear, cells are collected from a swab inserted into the anus. Those cells are then examined by a pathologist looking for pre-cancerous or dysplastic changes. Cytology (anal pap) negative or normal-when the pathologist examined the cells from the pap smear under a microscope, she found no abnormal cells or signs of hpv-related changesanal cytology is a fairly good indicator of who should be examined and who might have hsil, but it is not the best way to determine the severity of sil nor is it the best way to diagnose invasive anal cancer. Anal pap smears anal cancer & dysplasia screenings male anal pap smear tests. Anal pap smears (aka anal cytology) are screenings to help detect cancerous or precancerous cells in the anus. In addition to detecting signs of anal cancer, anal pap smears help determine a patients risk for other potentially related anal issues. An ascus pap smear is a pap smear result in which the patient has a benign level of abnormality in her cervical cells. Ascus stands for atypical squamous cells of undetermined significance. Having an ascus result does not necessarily mean disease is present. It does mean the test has uncovered a few cells which deviate from a normal cellular appearance. Although ascus can be caused by an early human papillomavirus (hpv) infection, an ascus diagnosis may also be due to irritation from sex or even bad pap smear technique. Diagnoses of ascus will often resolve spontaneously over time with no intervention or. Anal cytology (ie, the anal pap test) has been recommended by several research groups for screening at-risk populations for anal cancer this test is adapted from the principles of cervical screening. 16 in specific populations, anal cytology has been projected as a cost-effective way to prevent the occurrence of anal cancer and manage its. If you have an abnormal cervical cancer screening test result, you may need further testing. The following tests may be done depending on your age and your initial pap test result (see table 1 ) repeat pap test or co-testa repeat pap test or a repeat co-test (pap test and a test for high-risk types of hpv) is recommended as a follow-up to. Anal cancer this page is intended to provide information about anal cancer and its precursors, high grade and low grade anal squamous intraepithelial lesions (hsil and lsil respectively). You will also find information on human papilloma virus ( hpv ), the cause of over 90 of anal cancers. If hpv testing is unavailable, an alternative strategy is to repeat the pap smear at 4- to 6-month intervals. After 2 negative pap smears are obtained, usual screening may resume. But if either of the repeat pap smears results in ascus or worse, the woman should be referred for colposcopy (sor b).