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  anal cancer is rare in people younger than 35 and is found mainly in older adults, with an average age being in the early 60s. The risk of being diagnosed with anal cancer during ones lifetime is about 1 in 500. The risk is also higher in people with certain risk factors for anal cancer. Most anal cancers (80) are diagnosed in people who are over age 60. However, after age 50, anal cancer is slightly more common in women. Anal cancer incidence is strongly related to age, with the highest incidence rates being in older people. In the uk in 2015-2017, on average each year a quarter of new cases (25) were in people aged 75 and over. Age-specific incidence rates rise sharply from around age 35-39, slightly more rapidly for females than males. The highest rates are in in the 90 age group for females and males. Chronic local inflammation those with anal fistulas or open wounds that last a long time, have a slightly higher risk for developing anal cancer. Age two-thirds of anal cancer cases occur in people older than 55. The average age of diagnosis for anal cancer is in the early 60s. It is estimated that 1,350 deaths (540 men and 810 women) from this disease will occur this year. The 5-year survival rate tells you what percent of people live at least 5 years after the cancer is found. Using statistical models for analysis, age-adjusted rates for new anal cancer cases have been rising on average 2. What causes anal cancer? Nearly all (90) anal cancers are attributable to persistent infection with hpv, the cause of genital warts. Certain strains of hpv are known to be oncogenic (cancer-causing), especially types hpv 16 and 18, and these two infections cause more than 90 of anal cancers. Rarely, subtyping of hpv has detected low-risk strains such as hpv 6 or multiple strains of hpv.

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